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Anti-Tumor Activity of Orally Administered Gefitinib-Loaded Nanosized Cubosomes against Colon Cancer

Gefitinib (GFT) is a tyrosine kinase inhibitor drug used as a first-line treatment for patients with advanced or metastatic non-small cell lung, colon, and breast cancer. GFT exhibits low solubility and hence low oral bioavailability, which restricts its clinical application. One of the most importa...

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Detalles Bibliográficos
Autores principales: El-Shenawy, Ahmed A., Elsayed, Mahmoud M. A., Atwa, Gamal M. K., Abourehab, Mohammed A. S., Mohamed, Mohamed S., Ghoneim, Mohammed M., Mahmoud, Reda A., Sabry, Shereen A., Anwar, Walid, El-Sherbiny, Mohamed, Hassan, Yasser A., Belal, Amany, Ramadan, Abd El hakim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960579/
https://www.ncbi.nlm.nih.gov/pubmed/36840004
http://dx.doi.org/10.3390/pharmaceutics15020680