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Anti-Tumor Activity of Orally Administered Gefitinib-Loaded Nanosized Cubosomes against Colon Cancer
Gefitinib (GFT) is a tyrosine kinase inhibitor drug used as a first-line treatment for patients with advanced or metastatic non-small cell lung, colon, and breast cancer. GFT exhibits low solubility and hence low oral bioavailability, which restricts its clinical application. One of the most importa...
Autores principales: | El-Shenawy, Ahmed A., Elsayed, Mahmoud M. A., Atwa, Gamal M. K., Abourehab, Mohammed A. S., Mohamed, Mohamed S., Ghoneim, Mohammed M., Mahmoud, Reda A., Sabry, Shereen A., Anwar, Walid, El-Sherbiny, Mohamed, Hassan, Yasser A., Belal, Amany, Ramadan, Abd El hakim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960579/ https://www.ncbi.nlm.nih.gov/pubmed/36840004 http://dx.doi.org/10.3390/pharmaceutics15020680 |
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