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Effect of Span 20 Feeding Zone in the Twin Screw Extruder on the Properties of Amorphous Solid Dispersion of Ritonavir

A ternary amorphous solid dispersion (ASD) system consisting of drug/polymer/surfactant is receiving increased attention to improve the oral bioavailability of poorly water-soluble drugs. The effect of polymers has been extensively studied, while the impact of surfactants has not yet to be studied t...

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Detalles Bibliográficos
Autores principales: Wu, Hengqian, Wang, Zhengping, Zhao, Yanna, Gao, Yan, Zhang, Heng, Wang, Lili, Wang, Zhe, Han, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960583/
https://www.ncbi.nlm.nih.gov/pubmed/36839764
http://dx.doi.org/10.3390/pharmaceutics15020441