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Effect of Span 20 Feeding Zone in the Twin Screw Extruder on the Properties of Amorphous Solid Dispersion of Ritonavir
A ternary amorphous solid dispersion (ASD) system consisting of drug/polymer/surfactant is receiving increased attention to improve the oral bioavailability of poorly water-soluble drugs. The effect of polymers has been extensively studied, while the impact of surfactants has not yet to be studied t...
Autores principales: | Wu, Hengqian, Wang, Zhengping, Zhao, Yanna, Gao, Yan, Zhang, Heng, Wang, Lili, Wang, Zhe, Han, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960583/ https://www.ncbi.nlm.nih.gov/pubmed/36839764 http://dx.doi.org/10.3390/pharmaceutics15020441 |
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