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Considerations for Intravenous Anesthesia Dose in Obese Children: Understanding PKPD
The intravenous induction or loading dose in children is commonly prescribed per kilogram. That dose recognizes the linear relationship between volume of distribution and total body weight. Total body weight comprises both fat and fat-free mass. Fat mass influences the volume of distribution and the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960599/ https://www.ncbi.nlm.nih.gov/pubmed/36836174 http://dx.doi.org/10.3390/jcm12041642 |