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Novel Silver Complexes Based on Phosphanes and Ester Derivatives of Bis(pyrazol-1-yl)acetate Ligands Targeting TrxR: New Promising Chemotherapeutic Tools Relevant to SCLC Management

Bis(pyrazol-1-yl)acetic acid (HC(pz)(2)COOH) and bis(3,5-dimethyl-pyrazol-1-yl)acetic acid (HC(pz(Me2))(2)COOH) were converted into the methyl ester derivatives 1 (L(OMe)) and 2 (L(2OMe)), respectively, and were used for the preparation of silver(I) complexes 3–5. The Ag(I) complexes were prepared b...

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Detalles Bibliográficos
Autores principales: Pellei, Maura, Santini, Carlo, Bagnarelli, Luca, Caviglia, Miriam, Sgarbossa, Paolo, De Franco, Michele, Zancato, Mirella, Marzano, Cristina, Gandin, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960633/
https://www.ncbi.nlm.nih.gov/pubmed/36835512
http://dx.doi.org/10.3390/ijms24044091