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Intravital Microscopy Reveals Endothelial Transcytosis Contributing to Significant Tumor Accumulation of Albumin Nanoparticles

The principle of enhanced permeability and retention (EPR) effect has been used to design anti-cancer nanomedicines over decades. However, it is being challenged due to the poor clinical outcome of nanoparticles and controversial physiological foundation. Herein, we use a near-infrared-II (1000–1700...

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Detalles Bibliográficos
Autores principales: Wei, Guoguang, Zhang, Sihang, Yu, Sheng, Lu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960641/
https://www.ncbi.nlm.nih.gov/pubmed/36839841
http://dx.doi.org/10.3390/pharmaceutics15020519