Nicotine-Mediated Recruitment of GABAergic Neurons to a Dopaminergic Phenotype Attenuates Motor Deficits in an Alpha-Synuclein Parkinson’s Model

Previous work revealed an inverse correlation between tobacco smoking and Parkinson’s disease (PD) that is associated with nicotine-induced neuroprotection of dopaminergic (DA) neurons against nigrostriatal damage in PD primates and rodent models. Nicotine, a neuroactive component of tobacco, can di...

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Detalles Bibliográficos
Autores principales: Lai, Jessica IChi, Porcu, Alessandra, Romoli, Benedetto, Keisler, Maria, Manfredsson, Fredric P., Powell, Susan B., Dulcis, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960650/
https://www.ncbi.nlm.nih.gov/pubmed/36835612
http://dx.doi.org/10.3390/ijms24044204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960650/
https://www.ncbi.nlm.nih.gov/pubmed/36835612
http://dx.doi.org/10.3390/ijms24044204

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