Pharmacological Ischemic Conditioning with Roxadustat Does Not Affect Pain-Like Behaviors but Mitigates Sudomotor Impairment in a Murine Model of Deep Hind Paw Incision

PURPOSE: The involvement of hypoxic response mechanisms in local functional impairments in surgical wounds is unclear. In the present study, we characterized tissue hypoxia in surgical wounds and investigated the role of pharmacological ischemic conditioning (PIC) using roxadustat, an oral prolyl hy...

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Detalles Bibliográficos
Autores principales: Lu, Fanglin, Kato, Jungo, Toramaru, Tomoko, Zhang, Mengting, Morisaki, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960722/
https://www.ncbi.nlm.nih.gov/pubmed/36852095
http://dx.doi.org/10.2147/JPR.S397054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960722/
https://www.ncbi.nlm.nih.gov/pubmed/36852095
http://dx.doi.org/10.2147/JPR.S397054

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