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Stability of APOBEC3F in the Presence of the APOBEC3 Antagonist HIV-1 Vif Increases at the Expense of Co-Expressed APOBEC3H Haplotype I

The seven human APOBEC3 enzymes (APOBEC3A through H, excluding E) are host restriction factors. Most of the APOBEC3 enzymes can restrict HIV-1 replication with different efficiencies. The HIV-1 Vif protein combats APOBEC3-mediated restriction by inducing ubiquitination and degradation in the proteas...

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Detalles Bibliográficos
Autores principales: Yousefi, Maria, Annan Sudarsan, Arun Kumar, Gaba, Amit, Chelico, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960753/
https://www.ncbi.nlm.nih.gov/pubmed/36851677
http://dx.doi.org/10.3390/v15020463