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Novel Silicone-Grafted Alginate as a Drug Delivery Scaffold: Pharmaceutical Characterization of Gliclazide-Loaded Silicone-Based Composite Microcapsules

A novel gliclazide-loaded elastomeric carbohydrate pharmaceutical vehicle was successfully developed. This new siliconized alginate platform showed pseudoplastic rheology with a zeta potential ranging from (−43.8 mV to −75.5 mV). A Buchi-B390 encapsulator was employed to formulate different types of...

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Detalles Bibliográficos
Autores principales: Gedawy, Ahmed, Luna, Giuseppe, Martinez, Jorge, Brown, Daniel, Al-Salami, Hani, Dass, Crispin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960830/
https://www.ncbi.nlm.nih.gov/pubmed/36839852
http://dx.doi.org/10.3390/pharmaceutics15020530