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The Role of Mitotic Slippage in Creating a “Female Pregnancy-like System” in a Single Polyploid Giant Cancer Cell

In our recent work, we observed that triple-negative breast cancer MDA-MB-231 cells respond to doxorubicin (DOX) via “mitotic slippage” (MS), discarding cytosolic damaged DNA during the process that provides their resistance to this genotoxic treatment. We also noted two populations of polyploid gia...

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Detalles Bibliográficos
Autores principales: Salmina, Kristine, Vainshelbaum, Ninel Miriam, Kreishmane, Madara, Inashkina, Inna, Cragg, Mark Steven, Pjanova, Dace, Erenpreisa, Jekaterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960874/
https://www.ncbi.nlm.nih.gov/pubmed/36834647
http://dx.doi.org/10.3390/ijms24043237