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IGFBP-6 Alters Mesenchymal Stromal Cell Phenotype Driving Dasatinib Resistance in Chronic Myeloid Leukemia

Chronic myeloid leukemia (CML), BCR-ABL1-positive, is classified as a myeloproliferative characterized by Philadelphia chromosome/translocation t(9;22) and proliferating granulocytes. Despite the clinical success of tyrosine kinase inhibitors (TKi) agents in the treatment of CML, most patients have...

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Detalles Bibliográficos
Autores principales: Cambria, Daniela, Longhitano, Lucia, La Spina, Enrico, Giallongo, Sebastiano, Orlando, Laura, Giuffrida, Rosario, Tibullo, Daniele, Fontana, Paolo, Barbagallo, Ignazio, Nicoletti, Vincenzo Giuseppe, Volti, Giovanni Li, Fabro, Vittorio Del, Coda, Anna Rita Daniela, Liso, Arcangelo, Palumbo, Giuseppe Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960877/
https://www.ncbi.nlm.nih.gov/pubmed/36836615
http://dx.doi.org/10.3390/life13020259