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Selenium-modified bone cement promotes osteoporotic bone defect repair in ovariectomized rats by restoring GPx1-mediated mitochondrial antioxidant functions

Over-accumulation of reactive oxygen species (ROS) causes mitochondrial dysfunction and impairs the osteogenic potential of bone marrow-derived mesenchymal stem cells (BMMSCs). Selenium (Se) protects BMMSCs from oxidative stress-induced damage; however, it is unknown whether Se supplementation can p...

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Detalles Bibliográficos
Autores principales: Zhou, Quan, Chen, Weikai, Gu, Chao, Liu, Hao, Hu, Xiayu, Deng, Lei, He, Wei, Xu, Yong, Zhu, Xuesong, Yang, Huilin, Chen, Xi, He, Fan, Liu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960915/
https://www.ncbi.nlm.nih.gov/pubmed/36852397
http://dx.doi.org/10.1093/rb/rbad011