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Copper(II) Chelates of Schiff Bases Enriched with Aliphatic Fragments: Synthesis, Crystal Structure, In Silico Studies of ADMET Properties and a Potency against a Series of SARS-CoV-2 Proteins

We report two complexes [Cu(L(I))(2)] (1) and [Cu(L(II))(2)] (2) (HL(I) = N-cyclohexyl-3-methoxysalicylideneimine, HL(II) = N-cyclohexyl-3-ethoxysalicylideneimine). The ligands in both complexes are trans-1,5-N,O-coordinated, yielding a square planar CuN(2)O(2) coordination core. The molecule of 1 i...

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Detalles Bibliográficos
Autores principales: Panova, Elizaveta V., Voronina, Julia K., Safin, Damir A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960933/
https://www.ncbi.nlm.nih.gov/pubmed/37259430
http://dx.doi.org/10.3390/ph16020286