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Copper(II) Chelates of Schiff Bases Enriched with Aliphatic Fragments: Synthesis, Crystal Structure, In Silico Studies of ADMET Properties and a Potency against a Series of SARS-CoV-2 Proteins
We report two complexes [Cu(L(I))(2)] (1) and [Cu(L(II))(2)] (2) (HL(I) = N-cyclohexyl-3-methoxysalicylideneimine, HL(II) = N-cyclohexyl-3-ethoxysalicylideneimine). The ligands in both complexes are trans-1,5-N,O-coordinated, yielding a square planar CuN(2)O(2) coordination core. The molecule of 1 i...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960933/ https://www.ncbi.nlm.nih.gov/pubmed/37259430 http://dx.doi.org/10.3390/ph16020286 |