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Cisplatin-Loaded Thermosensitive Liposomes Functionalized with Hyaluronic Acid: Cytotoxicity and In Vivo Acute Toxicity Evaluation

Cisplatin (CDDP) is a potent antitumor drug used in first-line chemotherapy against several solid tumors, including breast cancer. However, toxicities and drug resistance limit its clinical application. Thermosensitive liposome (TSL) functionalized with hyaluronic acid (HA) containing cisplatin (TSL...

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Detalles Bibliográficos
Autores principales: Gomes, Isabela Pereira, Silva, Juliana de Oliveira, Cassali, Geovanni Dantas, De Barros, André Luís Branco, Leite, Elaine Amaral
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961010/
https://www.ncbi.nlm.nih.gov/pubmed/36839905
http://dx.doi.org/10.3390/pharmaceutics15020583