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Glucose 6-P Dehydrogenase Overexpression Improves Aging-Induced Endothelial Dysfunction in Aorta from Mice: Role of Arginase II

The increase of vascular arginase activity during aging causes endothelial dysfunction. This enzyme competes with the endothelial nitric oxide synthase (eNOS) for L-arginine substrate. Our hypothesis is that glucose 6-P dehydrogenase (G6PD) overexpression could improve the endothelial function modul...

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Detalles Bibliográficos
Autores principales: Serna, Eva, Mauricio, Maria D, San-Miguel, Teresa, Guerra-Ojeda, Sol, Verdú, David, Valls, Alicia, Arc-Chagnaud, Coralie, De la Rosa, Adrián, Viña, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961129/
https://www.ncbi.nlm.nih.gov/pubmed/36835034
http://dx.doi.org/10.3390/ijms24043622