Virtual Clinical Trials Guided Design of an Age-Appropriate Formulation and Dosing Strategy of Nifedipine for Paediatric Use

The rapid onset of action of nifedipine causes a precipitous reduction in blood pressure leading to adverse effects associated with reflex sympathetic nervous system (SNS) activation, including tachycardia and worsening myocardial and cerebrovascular ischemia. As a result, short acting nifedipine pr...

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Detalles Bibliográficos
Autores principales: Khan, Dilawar, Badhan, Raj, Kirby, Daniel J., Bryson, Simon, Shah, Maryam, Mohammed, Afzal Rahman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961156/
https://www.ncbi.nlm.nih.gov/pubmed/36839878
http://dx.doi.org/10.3390/pharmaceutics15020556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961156/
https://www.ncbi.nlm.nih.gov/pubmed/36839878
http://dx.doi.org/10.3390/pharmaceutics15020556

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