Infection of Pro- and Anti-Inflammatory Macrophages by Wild Type and Vaccine Strains of Measles Virus: NLRP3 Inflammasome Activation Independent of Virus Production

In humans and non-human primates, wild type (WT) measles virus (MeV) replicates extensively in lymphoid tissue and induces an innate response characteristic of NF-κB and inflammasome activation without type I interferon. In contrast, the live attenuated MeV vaccine (LAMV) replicates poorly in lympho...

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Detalles Bibliográficos
Autores principales: Suwanmanee, San, Ghimire, Shristi, Edwards, Jerome, Griffin, Diane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961283/
https://www.ncbi.nlm.nih.gov/pubmed/36851476
http://dx.doi.org/10.3390/v15020260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961283/
https://www.ncbi.nlm.nih.gov/pubmed/36851476
http://dx.doi.org/10.3390/v15020260

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