Pt(II)-PLGA Hybrid in a pH-Responsive Nanoparticle System Targeting Ovarian Cancer

Platinum-based agents are the main treatment option in ovarian cancer (OC). Herein, we report a poly(lactic-co-glycolic acid) (PLGA) nanoparticle (NP) encapsulating platinum (II), which is targeted to a cell-spanning protein overexpressed in above 90% of late-stage OC, mucin 1 (MUC1). The NP is coat...

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Detalles Bibliográficos
Autores principales: Wlodarczyk, Marek T., Dragulska, Sylwia A., Chen, Ying, Poursharifi, Mina, Acosta Santiago, Maxier, Martignetti, John A., Mieszawska, Aneta J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961376/
https://www.ncbi.nlm.nih.gov/pubmed/36839929
http://dx.doi.org/10.3390/pharmaceutics15020607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961376/
https://www.ncbi.nlm.nih.gov/pubmed/36839929
http://dx.doi.org/10.3390/pharmaceutics15020607

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