Gsmtx4 Alleviated Osteoarthritis through Piezo1/Calcineurin/NFAT1 Signaling Axis under Excessive Mechanical Strain

Excessive mechanical strain is the prominent risk factor for osteoarthritis (OA), causing cartilage destruction and degeneration. However, the underlying molecular mechanism contributing to mechanical signaling transduction remains unclear in OA. Piezo type mechanosensitive ion channel component 1 (...

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Detalles Bibliográficos
Autores principales: Ren, Xunshan, Zhuang, Huangming, Li, Bin, Jiang, Fuze, Zhang, Yuelong, Zhou, Panghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961447/
https://www.ncbi.nlm.nih.gov/pubmed/36835440
http://dx.doi.org/10.3390/ijms24044022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961447/
https://www.ncbi.nlm.nih.gov/pubmed/36835440
http://dx.doi.org/10.3390/ijms24044022

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