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Targeting the Endoplasmic Reticulum Stress-Linked PERK/GRP78/CHOP Pathway with Magnesium Sulfate Attenuates Chronic-Restraint-Stress-Induced Depression-like Neuropathology in Rats

Magnesium sulfate has demonstrated marked neuroprotection in eclampsia, hypoxia, stroke, and post-traumatic brain injury rodent models. However, its potential impact against chronic-restraint-stress (CRS)-induced depression-like neuropathology and associated alterations in endoplasmic reticulum (ER)...

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Detalles Bibliográficos
Autores principales: Arab, Hany H., Khames, Ali, Alsufyani, Shuruq E., El-Sheikh, Azza A. K., Gad, Amany M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961498/
https://www.ncbi.nlm.nih.gov/pubmed/37259443
http://dx.doi.org/10.3390/ph16020300