Cargando…

Targeting the Endoplasmic Reticulum Stress-Linked PERK/GRP78/CHOP Pathway with Magnesium Sulfate Attenuates Chronic-Restraint-Stress-Induced Depression-like Neuropathology in Rats

Magnesium sulfate has demonstrated marked neuroprotection in eclampsia, hypoxia, stroke, and post-traumatic brain injury rodent models. However, its potential impact against chronic-restraint-stress (CRS)-induced depression-like neuropathology and associated alterations in endoplasmic reticulum (ER)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Arab, Hany H., Khames, Ali, Alsufyani, Shuruq E., El-Sheikh, Azza A. K., Gad, Amany M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961498/ https://www.ncbi.nlm.nih.gov/pubmed/37259443 http://dx.doi.org/10.3390/ph16020300

Ejemplares similares

Meloxicam Targets COX-2/NOX1/NOX4/Nrf2 Axis to Ameliorate the Depression-like Neuropathology Induced by Chronic Restraint Stress in Rats
por: Arab, Hany H., et al.
Publicado: (2023)

Atractylenolide III Attenuates Apoptosis in H9c2 Cells by Inhibiting Endoplasmic Reticulum Stress through the GRP78/PERK/CHOP Signaling Pathway
por: Zuo, Meng-yu, et al.
Publicado: (2022)

Levels of circulating GRP78 and CHOP in endoplasmic reticulum stress pathways in Chinese type 2 diabetic kidney disease patients
por: Ma, Ning, et al.
Publicado: (2021)

The diagnostic value of endoplasmic reticulum stress-related specific proteins GRP78 and CHOP in patients with sepsis: a diagnostic cohort study
por: Li, Fangfang, et al.
Publicado: (2022)

Neuroprotective Impact of Linagliptin against Cadmium-Induced Cognitive Impairment and Neuropathological Aberrations: Targeting SIRT1/Nrf2 Axis, Apoptosis, and Autophagy
por: Arab, Hany H., et al.
Publicado: (2023)

Esophageal cancer stem cells reduce hypoxia-induced apoptosis by inhibiting the GRP78-perk-eIF2α-ATF4-CHOP pathway in vitro
por: Lin, Ruijiang, et al.
Publicado: (2023)

GRP78: A cell's response to stress
por: Ibrahim, Ibrahim M., et al.
Publicado: (2019)

EGFR confers radioresistance in human oropharyngeal carcinoma by activating endoplasmic reticulum stress signaling PERK‐eIF2α‐GRP94 and IRE1α‐XBP1‐GRP78
por: Zhang, Miao, et al.
Publicado: (2018)

A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway
por: Yuan, Hongyu, et al.
Publicado: (2022)

Hydroxytyrosol and olive leaf extract exert cardioprotective effects by inhibiting GRP78 and CHOP expression
por: Wu, Li-xing, et al.
Publicado: (2018)

The Protective Effect of the Endoplasmic Reticulum Stress-Related Factors BiP/GRP78 and CHOP/Gadd153 on Noise-induced Hearing Loss in Guinea Pigs
por: Xue, Qiuhong, et al.
Publicado: (2016)

Secretion of the endoplasmic reticulum stress protein, GRP78, into the BALF is increased in cigarette smokers
por: Aksoy, Mark O., et al.
Publicado: (2017)

Porcine Circovirus 2 Deploys PERK Pathway and GRP78 for Its Enhanced Replication in PK-15 Cells
por: Zhou, Yingshan, et al.
Publicado: (2016)

Endoplasmic Reticulum Stress PERK-ATF4-CHOP Pathway Is Associated with Hypothalamic Neuronal Injury in Different Durations of Stress in Rats
por: Yi, Shanyong, et al.
Publicado: (2017)

DiDang Tang Inhibits Endoplasmic Reticulum Stress-Mediated Apoptosis Induced by Oxygen Glucose Deprivation and Intracerebral Hemorrhage Through Blockade of the GRP78-IRE1/PERK Pathways
por: Huang, Qingxia, et al.
Publicado: (2018)

Characterizing Cell Stress and GRP78 in Glioma to Enhance Tumor Treatment
por: Liu, Kristie, et al.
Publicado: (2020)

Endoplasmic Reticulum Stress Increases DUSP5 Expression via PERK-CHOP Pathway, Leading to Hepatocyte Death
por: Jo, Hye Jin, et al.
Publicado: (2019)

Suppression of ER-stress induction of GRP78 as an anti-neoplastic mechanism of the cardiac glycoside Lanatoside C in pancreatic cancer: Lanatoside C suppresses GRP78 stress induction
por: Ha, Dat P., et al.
Publicado: (2021)

d-Pinitol protects against endoplasmic reticulum stress and apoptosis in hepatic ischemia-reperfusion injury via modulation of AFT4-CHOP/GRP78 and caspase-3 signaling pathways
por: Yan, Lei, et al.
Publicado: (2021)

GRP78 in lung cancer
por: Xia, Shengkai, et al.
Publicado: (2021)

Regulation of PERK Signaling and Leukemic Cell Survival by a Novel Cytosolic Isoform of the UPR Regulator GRP78/BiP
por: Ni, Min, et al.
Publicado: (2009)

Mild Endoplasmic Reticulum Stress Promotes Retinal Neovascularization via Induction of BiP/GRP78
por: Nakamura, Shinsuke, et al.
Publicado: (2013)

Endoplasmic Reticulum Stress-Associated Chaperones, Bip/GRP78 and Calnexin are Overexpressed in Keratocystic Odontogenic Tumours
por: Pavli, Maria, et al.
Publicado: (2014)

Regulation of the Endoplasmic Reticulum Stress by BIP/GRP78 is involved in Meiotic Maturation of Porcine Oocytes In Vitro
por: Park, Hyo-Jin, et al.
Publicado: (2017)

EGCG Enhances the Chemosensitivity of Colorectal Cancer to Irinotecan through GRP78-MediatedEndoplasmic Reticulum Stress
por: Wu, Wenbing, et al.
Publicado: (2022)

Glucose-Regulated Protein 78 (Grp78) Confers Chemoresistance to Tumor Endothelial Cells under Acidic Stress
por: Visioli, Fernanda, et al.
Publicado: (2014)

Relevance of serum levels of the endoplasmic reticulum stress protein GRP78 (glucose-regulated protein 78 kDa) as biomarker in pulmonary diseases
por: Al Zaidi, Muntadher, et al.
Publicado: (2023)

The interaction between SPARC and GRP78 interferes with ER stress signaling and potentiates apoptosis via PERK/eIF2α and IRE1α/XBP-1 in colorectal cancer
por: Chern, Yi-Jye, et al.
Publicado: (2019)

RCN1 suppresses ER stress-induced apoptosis via calcium homeostasis and PERK–CHOP signaling
por: Xu, S, et al.
Publicado: (2017)

Clusterin Protects Hepatocellular Carcinoma Cells from Endoplasmic Reticulum Stress Induced Apoptosis through GRP78
por: Wang, Cun, et al.
Publicado: (2013)

Tunicamycin promotes metastasis through upregulating endoplasmic reticulum stress induced GRP78 expression in thyroid carcinoma
por: Zhao, Guohong, et al.
Publicado: (2020)

XAF1 drives apoptotic switch of endoplasmic reticulum stress response through destabilization of GRP78 and CHIP
por: Lee, Kyung-Woo, et al.
Publicado: (2022)

Effects of GRP78 on Endoplasmic Reticulum Stress and Inflammatory Response in Macrophages of Large Yellow Croaker (Larimichthys crocea)
por: Sun, Jie, et al.
Publicado: (2023)

Mitochondrial metabolic regulation by GRP78
por: Prasad, Manoj, et al.
Publicado: (2017)

The stress-inducible molecular chaperone GRP78 as potential therapeutic target for coronavirus infection
por: Ha, Dat P., et al.
Publicado: (2020)

Differential requirement of GRP94 and GRP78 in mammary gland development
por: Zhu, Genyuan, et al.
Publicado: (2014)

Hydrogen sulfide inhibits endoplasmic reticulum stress through the GRP78/mTOR pathway in rat chondrocytes subjected to oxidative stress
por: Wu, Jianjun, et al.
Publicado: (2021)

Ultrasensitive Detection of GRP78 in Exosomes and Observation of Migration and Proliferation of Cancer Cells by Application of GRP78-Containing Exosomes
por: Tsurusawa, Naoko, et al.
Publicado: (2022)

GRP78-CAR T cell effector function against solid and brain tumors is controlled by GRP78 expression on T cells
por: Ibanez, Jorge, et al.
Publicado: (2023)

Depletion and Reversal of Hepatocellular Carcinoma Inducing CTL through ER Stress-Dependent PERK-CHOP Signaling Pathway
por: Guo, Mengnan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_tjle4544rql5f7tt649rdcb2vd