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Human Cytochrome P450 1, 2, 3 Families as Pharmacogenes with Emphases on Their Antimalarial and Antituberculosis Drugs and Prevalent African Alleles

Precision medicine gives individuals tailored medical treatment, with the genotype determining the therapeutic strategy, the appropriate dosage, and the likelihood of benefit or toxicity. Cytochrome P450 (CYP) enzyme families 1, 2, and 3 play a pivotal role in eliminating most drugs. Factors that af...

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Detalles Bibliográficos
Autores principales: Chamboko, Chiratidzo R., Veldman, Wayde, Tata, Rolland Bantar, Schoeberl, Birgit, Tastan Bishop, Özlem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961538/
https://www.ncbi.nlm.nih.gov/pubmed/36834793
http://dx.doi.org/10.3390/ijms24043383