Cargando…
Human Cytochrome P450 1, 2, 3 Families as Pharmacogenes with Emphases on Their Antimalarial and Antituberculosis Drugs and Prevalent African Alleles
Precision medicine gives individuals tailored medical treatment, with the genotype determining the therapeutic strategy, the appropriate dosage, and the likelihood of benefit or toxicity. Cytochrome P450 (CYP) enzyme families 1, 2, and 3 play a pivotal role in eliminating most drugs. Factors that af...
Autores principales: | Chamboko, Chiratidzo R., Veldman, Wayde, Tata, Rolland Bantar, Schoeberl, Birgit, Tastan Bishop, Özlem |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961538/ https://www.ncbi.nlm.nih.gov/pubmed/36834793 http://dx.doi.org/10.3390/ijms24043383 |
Ejemplares similares
-
Understanding the Pyrimethamine Drug Resistance Mechanism via Combined Molecular Dynamics and Dynamic Residue Network Analysis
por: Amusengeri, Arnold, et al.
Publicado: (2020) -
The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database
por: Gaedigk, Andrea, et al.
Publicado: (2017) -
In Vivo Modulation of Rat Liver Microsomal Cytochrome P450 Activity by Antimalarial, Anti-HIV, and Antituberculosis Plant Medicines
por: Appiah-Opong, Regina, et al.
Publicado: (2018) -
Integrated Computational Approaches and Tools for Allosteric Drug Discovery
por: Sheik Amamuddy, Olivier, et al.
Publicado: (2020) -
South African Abietane Diterpenoids and Their Analogs as Potential Antimalarials: Novel Insights from Hybrid Computational Approaches
por: Musyoka, Thommas, et al.
Publicado: (2019)