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Antimicrobial Peptide Mastoparan-AF Kills Multi-Antibiotic Resistant Escherichia coli O157:H7 via Multiple Membrane Disruption Patterns and Likely by Adopting 3–11 Amphipathic Helices to Favor Membrane Interaction

We investigated the antimicrobial activity and membrane disruption modes of the antimicrobial peptide mastoparan-AF against hemolytic Escherichia coli O157:H7. Based on the physicochemical properties, mastoparan-AF may potentially adopt a 3–11 amphipathic helix-type structure, with five to seven non...

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Detalles Bibliográficos
Autores principales: Lin, Chun-Hsien, Shyu, Ching-Lin, Wu, Zong-Yen, Wang, Chao-Min, Chiou, Shiow-Her, Chen, Jiann-Yeu, Tseng, Shu-Ying, Lin, Ting-Er, Yuan, Yi-Po, Ho, Shu-Peng, Tung, Kwong-Chung, Mao, Frank Chiahung, Lee, Han-Jung, Tu, Wu-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961542/
https://www.ncbi.nlm.nih.gov/pubmed/36837754
http://dx.doi.org/10.3390/membranes13020251