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Synthesis, Structural Elucidation, and Anti-Inflammatory Activity of a Water-Soluble Derivative of Arctiin

The poor oral bioavailability of arctiin caused by its low water solubility is the biggest obstacle in developing it as a drug. In this work, a new water-soluble glucuronide derivative of arctiin (arctigenin-4′-O-glucuronide) was synthesized through 2,2,6,6-tetramethylpiperidine 1-oxyl mediated oxid...

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Detalles Bibliográficos
Autores principales: Xu, Xia, Huang, Xiaofeng, Zheng, Yuedan, Wang, Xiaoling, Xie, Jing, Liu, Sha, Guo, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961579/
https://www.ncbi.nlm.nih.gov/pubmed/36838775
http://dx.doi.org/10.3390/molecules28041789