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Synthesis, Structural Elucidation, and Anti-Inflammatory Activity of a Water-Soluble Derivative of Arctiin
The poor oral bioavailability of arctiin caused by its low water solubility is the biggest obstacle in developing it as a drug. In this work, a new water-soluble glucuronide derivative of arctiin (arctigenin-4′-O-glucuronide) was synthesized through 2,2,6,6-tetramethylpiperidine 1-oxyl mediated oxid...
Autores principales: | Xu, Xia, Huang, Xiaofeng, Zheng, Yuedan, Wang, Xiaoling, Xie, Jing, Liu, Sha, Guo, Kun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961579/ https://www.ncbi.nlm.nih.gov/pubmed/36838775 http://dx.doi.org/10.3390/molecules28041789 |
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