MITF Downregulation Induces Death in Human Mast Cell Leukemia Cells and Impairs IgE-Dependent Degranulation

Activating mutations in KIT (CD117) have been associated with several diseases, including gastrointestinal stromal tumors and mastocytosis. Rapidly progressing pathologies or drug resistance highlight the need for alternative treatment strategies. Previously, we reported that the adaptor molecule SH...

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Detalles Bibliográficos
Autores principales: Proaño-Pérez, Elizabeth, Ollé, Laia, Guo, Yanru, Aparicio, Cristina, Guerrero, Mario, Muñoz-Cano, Rosa, Martin, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961600/
https://www.ncbi.nlm.nih.gov/pubmed/36834926
http://dx.doi.org/10.3390/ijms24043515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961600/
https://www.ncbi.nlm.nih.gov/pubmed/36834926
http://dx.doi.org/10.3390/ijms24043515

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