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Automated SSHHPS Analysis Predicts a Potential Host Protein Target Common to Several Neuroinvasive (+)ssRNA Viruses

Within the viral genome, short stretches of homologous host pathogen sequences (SSHHPS) span the protease cleavage sites. To identify host proteins that may be cleaved during infection, we searched the human proteome for viral protease cleavage sites (~20 amino acids). We developed a sequence-to-sym...

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Detalles Bibliográficos
Autores principales: Doctor, Katarina Z., Gilmour, Elizabeth, Recarte, Marilyn, Beatty, Trinity R., Shifa, Intisar, Stangel, Michaela, Schwisow, Jacob, Leary, Dagmar H., Legler, Patricia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961674/
https://www.ncbi.nlm.nih.gov/pubmed/36851756
http://dx.doi.org/10.3390/v15020542