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Mitochondrial-Targeted Triphenylphosphonium–Hydroxycamptothecin Conjugate and Its Nano-Formulations for Breast Cancer Therapy: In Vitro and In Vivo Investigation

Mitochondria are involved in various stages of cancer cell diffusion and metastasis. Therefore, targeting tumor mitochondria with antineoplastic medicines to cause mitochondria to initiate apoptosis may be an effective strategy for cancer therapy. Here, in order to enhance the anti-tumor efficacy of...

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Detalles Bibliográficos
Autores principales: Zhang, Kunfeng, Fu, Jingxin, Liu, Xiaorui, Guo, Yifei, Han, Meihua, Liu, Meifeng, Wang, Xiangtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961676/
https://www.ncbi.nlm.nih.gov/pubmed/36839710
http://dx.doi.org/10.3390/pharmaceutics15020388