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Mitochondrial-Targeted Triphenylphosphonium–Hydroxycamptothecin Conjugate and Its Nano-Formulations for Breast Cancer Therapy: In Vitro and In Vivo Investigation
Mitochondria are involved in various stages of cancer cell diffusion and metastasis. Therefore, targeting tumor mitochondria with antineoplastic medicines to cause mitochondria to initiate apoptosis may be an effective strategy for cancer therapy. Here, in order to enhance the anti-tumor efficacy of...
Autores principales: | Zhang, Kunfeng, Fu, Jingxin, Liu, Xiaorui, Guo, Yifei, Han, Meihua, Liu, Meifeng, Wang, Xiangtao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961676/ https://www.ncbi.nlm.nih.gov/pubmed/36839710 http://dx.doi.org/10.3390/pharmaceutics15020388 |
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