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Oncolytic Avian Reovirus σA-Modulated Upregulation of the HIF-1α/C-myc/glut1 Pathway to Produce More Energy in Different Cancer Cell Lines Benefiting Virus Replication

Our previous reports proved that the structural protein σA of avian reovirus (ARV) is an energy activator which can regulate cellular metabolism that is essential for virus replication. This study has further demonstrated that the ARV protein σA is able to upregulate the HIF-1α/myc/glut1 pathway in...

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Detalles Bibliográficos
Autores principales: Hsu, Chao-Yu, Huang, Jing-Wen, Huang, Wei-Ru, Chen, I-Chun, Chen, Ming-Shan, Liao, Tsai-Ling, Chang, Yu-Kang, Munir, Muhammad, Liu, Hung-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961784/
https://www.ncbi.nlm.nih.gov/pubmed/36851737
http://dx.doi.org/10.3390/v15020523