Characterization of Stable Pyrazole Derivatives of Curcumin with Improved Cytotoxicity on Osteosarcoma Cell Lines

Curcumin (CUR) is a natural molecule that is unstable due to the presence of a bis-ketone. To obtain more stable derivatives in biological fluids, the bis-ketone was replaced with pyrazole or O-substituted oximes. Their stability in solution was studied by UV–visible spectrophotometry. The effects o...

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Detalles Bibliográficos
Autores principales: Feriotto, Giordana, Rondanin, Riccardo, Marchetti, Paolo, Tagliati, Federico, Beninati, Simone, Tabolacci, Claudio, Grusi, Elisa, Aguzzi, Serena, Mischiati, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961829/
https://www.ncbi.nlm.nih.gov/pubmed/36836788
http://dx.doi.org/10.3390/life13020431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961829/
https://www.ncbi.nlm.nih.gov/pubmed/36836788
http://dx.doi.org/10.3390/life13020431

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