TMPRSS2 Is Essential for SARS-CoV-2 Beta and Omicron Infection

The COVID-19 pandemic remains a global health threat and novel antiviral strategies are urgently needed. SARS-CoV-2 employs the cellular serine protease TMPRSS2 for entry into lung cells, and TMPRSS2 inhibitors are being developed for COVID-19 therapy. However, the SARS-CoV-2 Omicron variant, which...

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Detalles Bibliográficos
Autores principales: Metzdorf, Kristin, Jacobsen, Henning, Greweling-Pils, Marina C., Hoffmann, Markus, Lüddecke, Tatjana, Miller, Felicitas, Melcher, Lars, Kempf, Amy M., Nehlmeier, Inga, Bruder, Dunja, Widera, Marek, Ciesek, Sandra, Pöhlmann, Stefan, Čičin-Šain, Luka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961888/
https://www.ncbi.nlm.nih.gov/pubmed/36851486
http://dx.doi.org/10.3390/v15020271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961888/
https://www.ncbi.nlm.nih.gov/pubmed/36851486
http://dx.doi.org/10.3390/v15020271

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