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Structural and Immunoreactivity Properties of the SARS-CoV-2 Spike Protein upon the Development of an Inactivated Vaccine

Inactivated vaccines are promising tools for tackling the COVID-19 pandemic. We applied several protocols for SARS-CoV-2 inactivation (by β-propiolactone, formaldehyde, and UV radiation) and examined the morphology of viral spikes, protein composition of the preparations, and their immunoreactivity...

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Detalles Bibliográficos
Autores principales: Kordyukova, Larisa V., Moiseenko, Andrey V., Serebryakova, Marina V., Shuklina, Marina A., Sergeeva, Maria V., Lioznov, Dmitry A., Shanko, Andrei V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961907/
https://www.ncbi.nlm.nih.gov/pubmed/36851694
http://dx.doi.org/10.3390/v15020480