Cargando…

Structural and Immunoreactivity Properties of the SARS-CoV-2 Spike Protein upon the Development of an Inactivated Vaccine

Inactivated vaccines are promising tools for tackling the COVID-19 pandemic. We applied several protocols for SARS-CoV-2 inactivation (by β-propiolactone, formaldehyde, and UV radiation) and examined the morphology of viral spikes, protein composition of the preparations, and their immunoreactivity...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kordyukova, Larisa V., Moiseenko, Andrey V., Serebryakova, Marina V., Shuklina, Marina A., Sergeeva, Maria V., Lioznov, Dmitry A., Shanko, Andrei V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961907/ https://www.ncbi.nlm.nih.gov/pubmed/36851694 http://dx.doi.org/10.3390/v15020480

Ejemplares similares

COVID-19: Myths and Reality
por: Kordyukova, Larisa V., et al.
Publicado: (2021)

Comparative Immunological Study in Mice of Inactivated Influenza Vaccines Used in the Russian Immunization Program
por: Shanko, Andrei, et al.
Publicado: (2020)

Characterization of Inactivated Influenza Vaccines Used in the Russian National Immunization Program
por: Tarasov, Mikhail, et al.
Publicado: (2020)

Mass spectrometric approaches to study enveloped viruses: New possibilities for structural biology and prophylactic medicine
por: Kordyukova, L. V., et al.
Publicado: (2012)

Stearic acid blunts growth-factor signaling via oleoylation of GNAI proteins
por: Nůsková, Hana, et al.
Publicado: (2021)

Longitudinal Analysis of Neuraminidase and Hemagglutinin Antibodies to Influenza A Viruses after Immunization with Seasonal Inactivated Influenza Vaccines
por: Sergeeva, Mariia V., et al.
Publicado: (2023)

Immunogenic properties of SARS-CoV-2 inactivated by ultraviolet light
por: Gracheva, A. V., et al.
Publicado: (2022)

Genomic epidemiology of the early stages of the SARS-CoV-2 outbreak in Russia
por: Komissarov, Andrey B., et al.
Publicado: (2021)

Detection of the Omicron SARS-CoV-2 Lineage and Its BA.1 Variant with Multiplex RT-qPCR
por: Yolshin, Nikita D., et al.
Publicado: (2022)

The Cytoplasmic Tail of Influenza A Virus Hemagglutinin and Membrane Lipid Composition Change the Mode of M1 Protein Association with the Lipid Bilayer
por: Kordyukova, Larisa V., et al.
Publicado: (2021)

Investigation of the Role of PUFA Metabolism in Breast Cancer Using a Rank-Based Random Forest Algorithm
por: Guryleva, Mariia V., et al.
Publicado: (2022)

eIF4G2 balances its own mRNA translation via a PCBP2-based feedback loop
por: Smirnova, Victoria V., et al.
Publicado: (2019)

A Fusion Protein Based on the Second Subunit of Hemagglutinin of Influenza A/H2N2 Viruses Provides Cross Immunity
por: Stepanova, L. A., et al.
Publicado: (2016)

Size Distribution of Inactivated Tick-Borne Encephalitis Virus Particles Revealed by a Comprehensive Physicochemical Approach
por: Moiseenko, Andrey V., et al.
Publicado: (2022)

SARS-CoV-2 escape from cytotoxic T cells during long-term COVID-19
por: Stanevich, Oksana V., et al.
Publicado: (2023)

Spread of endemic SARS-CoV-2 lineages in Russia before April 2021
por: Klink, Galya V., et al.
Publicado: (2022)

Mold Alkaloid Cytochalasin D Modifies the Morphology and Secretion of fMLP-, LPS-, or PMA-Stimulated Neutrophils upon Adhesion to Fibronectin
por: Galkina, Svetlana I., et al.
Publicado: (2017)

Erratum to “Mold Alkaloid Cytochalasin D Modifies the Morphology and Secretion of fMLP-, LPS-, or PMA-Stimulated Neutrophils upon Adhesion to Fibronectin”
por: Galkina, Svetlana I., et al.
Publicado: (2018)

Two Cytoplasmic Acylation Sites and an Adjacent Hydrophobic Residue, but No Other Conserved Amino Acids in the Cytoplasmic Tail of HA from Influenza A Virus Are Crucial for Virus Replication
por: Siche, Stefanie, et al.
Publicado: (2015)

Comparison of PPAR Ligands as Modulators of Resolution of Inflammation, via Their Influence on Cytokines and Oxylipins Release in Astrocytes
por: Chistyakov, Dmitry V., et al.
Publicado: (2020)

High Glucose Shifts the Oxylipin Profiles in the Astrocytes towards Pro-Inflammatory States
por: Chistyakov, Dmitry V., et al.
Publicado: (2021)

IgGκ Signal Peptide Enhances the Efficacy of an Influenza Vector Vaccine against Respiratory Syncytial Virus Infection in Mice
por: Pulkina, Anastasia, et al.
Publicado: (2023)

Hybrid Proteins with Short Conformational Epitopes of the Receptor-Binding Domain of SARS-CoV-2 Spike Protein Promote Production of Virus-Neutralizing Antibodies When Used for Immunization
por: Karyagina, Anna S., et al.
Publicado: (2022)

Identification of Phytaspase Interactors via the Proximity-Dependent Biotin-Based Identification Approach
por: Teplova, Anastasia D., et al.
Publicado: (2021)

Inhibition of Neutrophil Secretion Upon Adhesion as a Basis for the Anti-Inflammatory Effect of the Tricyclic Antidepressant Imipramine
por: Galkina, Svetlana I., et al.
Publicado: (2021)

The rise and spread of the SARS-CoV-2 AY.122 lineage in Russia
por: Klink, Galya V., et al.
Publicado: (2021)

Bivalent omicron (BA.1) booster vaccination against SARS-CoV-2
por: Vasin, Andrey V, et al.
Publicado: (2023)

ARGEOS: A New Bioinformatic Tool for Detailed Systematics Search in GEO and ArrayExpress
por: Gavrish, Gleb E., et al.
Publicado: (2021)

Influence of the Linking Order of Fragments of HA2 and M2e of the influenza A Virus to Flagellin on the Properties of Recombinant Proteins
por: Stepanova, L. A., et al.
Publicado: (2018)

The rise and spread of the SARS-CoV-2 AY.122 lineage in Russia
por: Klink, Galya V, et al.
Publicado: (2022)

Sex-Mediated Differences in LPS Induced Alterations of TNFα, IL-10 Expression, and Prostaglandin Synthesis in Primary Astrocytes
por: Chistyakov, Dmitry V., et al.
Publicado: (2018)

High and Low Molecular Weight Hyaluronic Acid Differentially Influences Oxylipins Synthesis in Course of Neuroinflammation
por: Chistyakov, Dmitry V., et al.
Publicado: (2019)

Cellular Model of Endotoxin Tolerance in Astrocytes: Role of Interleukin 10 and Oxylipins
por: Chistyakov, Dmitry V., et al.
Publicado: (2019)

Antibodies to the Spike Protein Receptor-Binding Domain of SARS-CoV-2 at 4–13 Months after COVID-19
por: Kolosova, Evgeniia A., et al.
Publicado: (2022)

Free SARS-CoV-2 Spike Protein S1 Particles May Play a Role in the Pathogenesis of COVID-19 Infection
por: Letarov, Andrey V., et al.
Publicado: (2020)

Immunoreactive peptide maps of SARS-CoV-2
por: Mishra, Nischay, et al.
Publicado: (2021)

Inhibitor of Hyaluronic Acid Synthesis 4-Methylumbelliferone as an Anti-Inflammatory Modulator of LPS-Mediated Astrocyte Responses
por: Chistyakov, Dmitry V., et al.
Publicado: (2020)

Safety and Immunogenicity of Betuvax-CoV-2, an RBD-Fc-Based SARS-CoV-2 Recombinant Vaccine: Preliminary Results of the First-in-Human, Randomized, Double-Blind, Placebo-Controlled Phase I/II Clinical Trial
por: Kudriavtsev, Aleksandr V., et al.
Publicado: (2023)

Deuterated Arachidonic Acids Library for Regulation of Inflammation and Controlled Synthesis of Eicosanoids: An In Vitro Study
por: Chistyakov, Dmitry V., et al.
Publicado: (2018)

SARS-CoV-2 Spike Protein Interaction Space
por: Lungu, Claudiu N., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_4o8bttld2nm0tr2em4dqoomrpc