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Development of an RNase H2 Activity Assay for Clinical Screening

As the key enzyme mediating ribonucleotide excision repair, RNase H2 is essential for the removal of single ribonucleotides from DNA in order to prevent genome damage. Loss of RNase H2 activity directly contributes to the pathogenesis of autoinflammatory and autoimmune diseases and might further pla...

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Detalles Bibliográficos
Autores principales: Schulz, Marian Simon, Sartorius von Bach, Cay Bennet, Marinkovic, Emilija, Günther, Claudia, Behrendt, Rayk, Roers, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961991/
https://www.ncbi.nlm.nih.gov/pubmed/36836134
http://dx.doi.org/10.3390/jcm12041598