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Glioblastoma Multiforme: Probing Solutions to Systemic Toxicity towards High-Dose Chemotherapy and Inflammatory Influence in Resistance against Temozolomide

Temozolomide (TMZ), the first-line chemotherapeutic drug against glioblastoma multiforme (GBM), often fails to provide the desired clinical outcomes due to inflammation-induced resistance amid inefficient drug delivery across the blood-brain barrier (BBB). The current study utilized solid lipid nano...

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Detalles Bibliográficos
Autores principales: Nasir, Sadia, Nazir, Sadia, Hanif, Rumeza, Javed, Aneela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962012/
https://www.ncbi.nlm.nih.gov/pubmed/36840009
http://dx.doi.org/10.3390/pharmaceutics15020687