Metformin Directly Binds to MMP-9 to Improve Plaque Stability

Vulnerable atherosclerotic plaque rupture is the principal mechanism that accounts for myocardial infarction and stroke. High matrix metalloproteinase-9 (MMP-9) expression and activity have been proven to lead to plaque instability. Metformin, a first-line treatment for type 2 diabetes, is beneficia...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xianda, Wang, Shuaixing, Xu, Wenli, Zhao, Mingming, Zhang, Youyi, Xiao, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962015/
https://www.ncbi.nlm.nih.gov/pubmed/36826550
http://dx.doi.org/10.3390/jcdd10020054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962015/
https://www.ncbi.nlm.nih.gov/pubmed/36826550
http://dx.doi.org/10.3390/jcdd10020054

Ejemplares similares