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Inhibition of Hepatitis B Virus (HBV) by Tachyplesin, a Marine Antimicrobial Cell-Penetrating Peptide

We investigate the role of Tachyplesin (Tpl), a marine antimicrobial cell-penetrating peptide, as an anti-HBV agent. Our findings, using confocal microscopy and flow cytometry, demonstrate the internalization of FITC-Tpl in both Huh7 and HepG2 cell lines. Further, our results show that Tpl inhibits...

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Detalles Bibliográficos
Autores principales: Narula, Pankhuri, Kiruthika, Sankar, Chowdhari, Shruti, Vivekanandan, Perumal, Chugh, Archana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962029/
https://www.ncbi.nlm.nih.gov/pubmed/36839994
http://dx.doi.org/10.3390/pharmaceutics15020672