Synthesis and Characterization of Nanoparticle-Based Dexamethasone-Polypeptide Conjugates as Potential Intravitreal Delivery Systems

The use of dexamethasone for eye disease treatment is limited by its low solubility, bioavailability, and rapid elimination when applied topically. The covalent conjugation of dexamethasone with polymeric carriers is a promising strategy to overcome existing drawbacks. In this work, amphiphilic poly...

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Detalles Bibliográficos
Autores principales: Zashikhina, Natalia, Gladnev, Sergei, Sharoyko, Vladimir, Korzhikov-Vlakh, Viktor, Korzhikova-Vlakh, Evgenia, Tennikova, Tatiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962198/
https://www.ncbi.nlm.nih.gov/pubmed/36835114
http://dx.doi.org/10.3390/ijms24043702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962198/
https://www.ncbi.nlm.nih.gov/pubmed/36835114
http://dx.doi.org/10.3390/ijms24043702

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