Selectively Modified Lactose and N-Acetyllactosamine Analogs at Three Key Positions to Afford Effective Galectin-3 Ligands †

Galectins constitute a family of galactose-binding lectins overly expressed in the tumor microenvironment as well as in innate and adaptive immune cells, in inflammatory diseases. Lactose ((β-D-galactopyranosyl)-(1→4)-β-D-glucopyranose, Lac) and N-Acetyllactosamine (2-acetamido-2-deoxy-4-O-β-D-galac...

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Detalles Bibliográficos
Autores principales: Abdullayev, Shuay, Kadav, Priyanka, Bandyopadhyay, Purnima, Medrano, Francisco Javier, Rabinovich, Gabriel A., Dam, Tarun K., Romero, Antonio, Roy, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962200/
https://www.ncbi.nlm.nih.gov/pubmed/36835132
http://dx.doi.org/10.3390/ijms24043718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962200/
https://www.ncbi.nlm.nih.gov/pubmed/36835132
http://dx.doi.org/10.3390/ijms24043718

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