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Selectively Modified Lactose and N-Acetyllactosamine Analogs at Three Key Positions to Afford Effective Galectin-3 Ligands †
Galectins constitute a family of galactose-binding lectins overly expressed in the tumor microenvironment as well as in innate and adaptive immune cells, in inflammatory diseases. Lactose ((β-D-galactopyranosyl)-(1→4)-β-D-glucopyranose, Lac) and N-Acetyllactosamine (2-acetamido-2-deoxy-4-O-β-D-galac...
Autores principales: | Abdullayev, Shuay, Kadav, Priyanka, Bandyopadhyay, Purnima, Medrano, Francisco Javier, Rabinovich, Gabriel A., Dam, Tarun K., Romero, Antonio, Roy, René |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962200/ https://www.ncbi.nlm.nih.gov/pubmed/36835132 http://dx.doi.org/10.3390/ijms24043718 |
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