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Novel Inhibitors of Acetyl- and Butyrylcholinesterase Derived from Benzohydrazides: Synthesis, Evaluation and Docking Study

On the basis of previous reports, novel 2-benzoylhydrazine-1-carboxamides were designed as potential inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Inhibitors of these enzymes have many clinical applications. 2-(Substituted benzoyl)hydrazine-1-carboxamides decorated with...

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Detalles Bibliográficos
Autores principales: Houngbedji, Neto-Honorius, Štěpánková, Šárka, Pflégr, Václav, Svrčková, Katarína, Švarcová, Markéta, Vinšová, Jarmila, Krátký, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962224/
https://www.ncbi.nlm.nih.gov/pubmed/37259322
http://dx.doi.org/10.3390/ph16020172