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The Plant Derived 3-3′-Diindolylmethane (DIM) Behaves as CB(2) Receptor Agonist in Prostate Cancer Cellular Models

3-3′-Diindolylmethane (DIM) is a biologically active dimer derived from the endogenous conversion of indole-3-carbinol (I3C), a naturally occurring glucosinolate found in many cruciferous vegetables (i.e., Brassicaceae). DIM was the first pure androgen receptor antagonist isolated from the Brassicac...

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Detalles Bibliográficos
Autores principales: Tucci, Paolo, Brown, Iain, Bewick, Guy S., Pertwee, Roger G., Marini, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962283/
https://www.ncbi.nlm.nih.gov/pubmed/36835033
http://dx.doi.org/10.3390/ijms24043620