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Insightful Improvement in the Design of Potent Uropathogenic E. coli FimH Antagonists

Selective antiadhesion antagonists of Uropathogenic Escherichia coli (UPEC) type-1 Fimbrial adhesin (FimH) are attractive alternatives for antibiotic therapies and prophylaxes against acute or recurrent urinary tract infections (UTIs) caused by UPECs. A rational small library of FimH antagonists bas...

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Detalles Bibliográficos
Autores principales: Mousavifar, Leila, Sarshar, Meysam, Bridot, Clarisse, Scribano, Daniela, Ambrosi, Cecilia, Palamara, Anna Teresa, Vergoten, Gérard, Roubinet, Benoît, Landemarre, Ludovic, Bouckaert, Julie, Roy, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962304/
https://www.ncbi.nlm.nih.gov/pubmed/36839848
http://dx.doi.org/10.3390/pharmaceutics15020527