Cargando…
Insightful Improvement in the Design of Potent Uropathogenic E. coli FimH Antagonists
Selective antiadhesion antagonists of Uropathogenic Escherichia coli (UPEC) type-1 Fimbrial adhesin (FimH) are attractive alternatives for antibiotic therapies and prophylaxes against acute or recurrent urinary tract infections (UTIs) caused by UPECs. A rational small library of FimH antagonists bas...
Autores principales: | Mousavifar, Leila, Sarshar, Meysam, Bridot, Clarisse, Scribano, Daniela, Ambrosi, Cecilia, Palamara, Anna Teresa, Vergoten, Gérard, Roubinet, Benoît, Landemarre, Ludovic, Bouckaert, Julie, Roy, René |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962304/ https://www.ncbi.nlm.nih.gov/pubmed/36839848 http://dx.doi.org/10.3390/pharmaceutics15020527 |
Ejemplares similares
-
FimH and Anti-Adhesive Therapeutics: A Disarming Strategy Against Uropathogens
por: Sarshar, Meysam, et al.
Publicado: (2020) -
Comparative Study of Aryl O-, C-, and S-Mannopyranosides as Potential Adhesion Inhibitors toward Uropathogenic E. coli FimH
por: Mousavifar, Leila, et al.
Publicado: (2019) -
d-Mannose Treatment neither Affects Uropathogenic Escherichia coli Properties nor Induces Stable FimH Modifications
por: Scribano, Daniela, et al.
Publicado: (2020) -
Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors
por: Krammer, Eva-Maria, et al.
Publicado: (2023) -
A Novel Integrated Way for Deciphering the Glycan Code for the FimH Lectin
por: Dumych, Tetiana, et al.
Publicado: (2018)