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Effect of PEG Anchor and Serum on Lipid Nanoparticles: Development of a Nanoparticles Tracking Method

Polyethylene glycol (PEG) is used in Lipid Nanoparticles (LNPs) formulations to confer stealth properties and is traditionally anchored in membranes by a lipid moiety whose length significantly impacts the LNPs fate in vivo. C18 acyl chains are efficiently anchored in the membrane, while shorter C14...

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Detalles Bibliográficos
Autores principales: Berger, Manon, Degey, Manon, Leblond Chain, Jeanne, Maquoi, Erik, Evrard, Brigitte, Lechanteur, Anna, Piel, Géraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962341/
https://www.ncbi.nlm.nih.gov/pubmed/36839919
http://dx.doi.org/10.3390/pharmaceutics15020597