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Effect of Deferoxamine on Post-Transfusion Iron, Inflammation, and In Vitro Microbial Growth in a Canine Hemorrhagic Shock Model: A Randomized Controlled Blinded Pilot Study

SIMPLE SUMMARY: Blood transfusions can be lifesaving but can also harm patients by causing inflammation and increasing the risk of infection. Harm may occur from increasing the amount of unbound iron in circulation. When it is not bound to special carriers, iron is toxic, causing inflammation and su...

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Detalles Bibliográficos
Autores principales: Claus, Melissa A., Smart, Lisa, Raisis, Anthea L., Sharp, Claire R., Abraham, Sam, Gummer, Joel P. A., Mead, Martin K., Bradley, Damian L., Van Swelm, Rachel, Wiegerinck, Erwin T. G., Litton, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962370/
https://www.ncbi.nlm.nih.gov/pubmed/36851425
http://dx.doi.org/10.3390/vetsci10020121